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If positive, results from a first 100-patient trial - due any day now - will boost Sanofi's confidence in its drug, which may reach the market by 2015. But its ultimate success depends on longer-term studies involving thousands of patients, some of which will only produce results in around five years.
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In contrast, New Zealand's economy is on the up due toearthquake reconstruction projects in the Canterbury region ofthe South Island, while its high-tech manufacturing and ITsectors are expanding strongly.
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J.C. Penney Co Inc, which this week reported a 4percent drop in comparable sales for September but is not partof the same-store sales index, said traffic trends at its mallstores remained "difficult."
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Luke Donald shot a 72 to finish in a tie for ninth while Wales’s Jamie Donaldson and two other Englishmen in Ian Poulter and Justin Rose also came in the top 20. Rory McIlroy was down in a tie for 27th after his own 72. He came here to kick-start his spluttering campaign, just as he did last year when finishing fifth before winning the US PGA by eight shots. McIlroy faces a race against time to sort out his driving before Thursday’s first round.
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"But it's obvious that North Korea is a tough nut to crack and the U.N.'s means are limited. There would need to be profound political changes in North Korea to make headway in the field of human rights."

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When he was 16 he abandoned his education, having attended 12 different schools, and three years later his mother, an interior designer, managed to get him into a rehabilitation clinic. “I did the stint,” he recalled, “but then went back to doing exactly what I left off doing.”
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The study found that the risk of gestational diabetes did not fall among the exercise group, however, the risk of macrosomia did. Macrosomia refers to babies who are considered abnormally large before birth. They have a birth weight of at least four kilos (8lbs, 13ozs).
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But Bennett — who has recorded voiceovers used for GPS devices and terminals announcing Delta Airlines flights — was used to keeping her anonymity, even though several friends and relatives tried to get her to speak up.
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Samsung is widely expected to have sold 86-88 million smartphones in the third quarter, up from 76 million in the second quarter, as the company increased shipments of cheaper models to emerging markets.
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I plan on picking it up on PS3 first and later on for the Vita so a delay won’t bother me too much. That’s just me though, i imagine there will be many Vita owners disappointed if it’s true.

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Importantly, the researchers also found that the risk of early death in people with epilepsy compared with their unaffected siblings, and the risk of early death in people with epilepsy compared with general population, did not differ significantly. This suggests that epilepsy is an independent risk factor for all-cause and external causes of death.
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The Australian and Canadian dollars have been in demandsince the global financial crisis as relatively safe havens. Theaussie in particular was highly desired given its yield thoughenthusiasm has cooled compared with the loonie, based on theCOFER data.
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Saakashvili's presidential term does not end until October, but his authority has been further weakened by a constitutional reform that has shifted powers from the presidency to Parliament and the prime minister.
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Britain's government wants most of the country's homes to have smart meters by the end of the decade in a programme which aims to replace existing gas and electricity meters, saving the average household an estimated 65 pounds a year.
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The verdict was annulled for irregularities by the high military court in 2010, but a new panel of judges convicted them in a retrial in June that year of spying, criminal association, murder and attempted murder.

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It looks like the help to buy scheme is pushing up the market again which gives the perception that everyone is out buying houses with massive deposits but reality is most people are only buying an initial share of their home and pay rent on the remainder.We are a generation that now look to these loans because it seems the only way and that bubble looks set to burst
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Police took one person into custody following the shooting at the Gift Center and Jewelry Mart, a multi-story building in the city's South of Market neighborhood, and said they were conducting an extensive search for a possible second suspect.
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It has a clean blue-and-white design, and finds a good balance between corporate branding and accessibility. Considering BT is one of Rogers’ most popular shows, it makes sense to see this app on the iPhone first. It will also be rolling out to Android devices in the coming weeks.
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"There is no evidence of IRM/IA management engaging in a comprehensive strategic review to assess its current capabilities and future needs," the report says. "The CISO and his division chiefs have not reviewed operations to determine what information assurance and security functions they are required to perform or are currently handling."
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The Republican response, delivered by Representative Cathy McMorris Rodgers, focused not on a possible shutdown but on the next fight, over raising the government's borrowing authority, which runs out in mid-October.

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Social media is a pipeline for opinion. The very nature of Internet-sharing sites dictates that information gleaned from Facebook, blogs or Twitter — which is limited to 140 characters per post — is marinated in personal views and served with a sauce of bias.
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Chicago seems tailor-made to take advantage of the Giants. Big Blue has committed a league-leading 20 turnovers, and Chicago ranks second in the NFL with 14 takeaways. The Bears have a king-sized receiving tandem of Brandon Marshall and Alshon Jeffery; the Giants will be without top corner Corey Webster for a fourth straight game.
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However, please note - if you block/delete all cookies, some features of our websites, such as remembering your login details, or the site branding for your local newspaper may not function as a result.
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Tuesday, WhatsApp will attempt to conquer a new realm in messaging. The application is being updated with push-to-talk voice messaging so people can effortlessly weave audio recordings into their conversation threads -- potentially already populous with photos, videos, or locations -- with friends on the service. Members simply tap and hold the microphone icon to record a message that sends on release of the button, or they can slide their finger to the left to cancel the recording.
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The French forces, trapped in the valley, suffered a bombardment that lasted more than two months and lost 4,000 men before they surrendered in May, a victory which signalled the end of French colonial rule in the region.

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"After we taped, I would get an envelope with around $30 in it, and I would go buy Michael Jackson tapes for $1 or polo shirts for $2. I still have those show tapes in a box somewhere, but they will never see the light of day. They exist - and they're very funny."
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Finance Minister Lou Jiwei was quoted in a Xinhua interviewpublished late on Saturday saying that China is looking tobusiness tax reform and the easing of paperwork requirements tohelp stimulate growth and sustain profitability.
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The report said Snowden, now living in temporary asylum inRussia, attended the conference of the so-called Five Eyesintelligence-sharing network between the United States, Britain,Canada, Australia and New Zealand.
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Now, the caveat: The bennies only go for those who drink moderately, which is probably a lot less than you think. Case in point: The slim drinkers in the Archives study were served no more than two four-ounce glasses of wine or two 1.5-ounce shots of liquor a day. According to the National Institutes of Health, most bartenders serve glasses containing up to three times the alcohol they should, making it difficult for you to find the "two drink" sweet spot that most researchers opine is healthy for men.

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SAN DIEGO (AP) — Mayor Bob Filner is ending therapy earlier than he announced, his attorneys said late Friday, as the leader of the nation's eighth-largest city came under enormous pressure to resign amid sexual harassment allegations.
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Calls appreciate in value when the price of the shares rise. The timing of these select call trades could suggest that some people caught wind of the offer ahead of time. The Canadian newspaper Financial Post reported it on Friday, sparking a steep jump in Onyx shares in after-hours trading.
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“I saw a Michael that frightened me, a Michael that was shivering and cold,” Ortega told the jury hearing a wrongful death lawsuit brought by Michael's mom and kids against concert promoter AEG Live.
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The latter said on Thursday that second quarter same-storesales were impacted by the higher payroll tax, among otherfactors, while Macy's reported an unexpected decline in sales aday earlier, blaming hesitation by consumers to spend onnon-essential items.
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Asked if he sees any similarity between that unit and the defense he’s a part of now, the rookie said, “Most definitely, except the fact that I didn’t grow up with these guys. But the chemistry’s there. The brotherhood, the accountability, everything is there.”
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Even though Meyers realized his calling wasn’t in character acting, it didn’t stop him from co-creating “The Awesomes” with Michael Shoemaker, and voicing one of the characters alongside some “SNL” castmates.
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A Department of Health spokesman said: "We know that there are issues with how hospitals handle complaints and that's why we asked Ann Clwyd and Tricia Hart to carry out a review into the system.
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Stabilizing Performance: Similar to other timeshare originators and other consumer asset types, MVW's delinquency and default performance exhibited notable increases in the 2007 to 2009 vintages. However, the 2010 and 2011 vintages are displaying improved performance.
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Tesla's Model S, which can run 265 miles on a single charge, costs $71,000. GM aims to develop an electric car that can yield similar mileage as the Model S, but at a price that's about the same as its Chevrolet Volt.

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What was altogether more of a revelation was just how damaging, healthwise, the effect of this predicament has proved, with Gambon divulging that he had been hospitalised twice during rehearsals from Alan Bennett’s The Habit of Art at the National in 2009 (which he withdrew from) because of ailments which appear to have been brought on by panic.
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Chief Buster Varner of the Bartow-Frank-Durbin Volunteer Fire Department says Danny Lee Kimble Sr. of Frank was pronounced dead at the scene of Friday's accident along U.S. Route 250. Varner says he spoke to Kimble's son Saturday morning.
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The introduction of a new villain is a blatant attempt at a Freddy Krueger-style franchise fiend. A pair of goofy ghostbusters (Angus Sampson, Andrew Astor) return from the first film to lighten the mood, but get in the way. There’s also the reprise of the irritating Lin Shaye as a minor medium, along with a few other characters. There’s a loophole, apparently, to who must stay and who can wander back to the living.
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The 100-odd Twitter rant included such gems as: “I f****ed porn stars I met through my class”, “I cheated on my wife and pretended to be reformed”, and “I wrote an article in the Atlantic condemning age-disparate relationships the same week that I was sleeping with a 32-year-old. And sexting a 27-year-old”. And one more: “You can denounce me now, I’m out of feminism, not because I don’t believe in it, but because I’m such a p***poor [sic] example of it.”
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Silva entered the fight 33-4, with a UFC-record 10 straight title defenses, to go with his undefeated 16-0 record since joining the UFC. Weidman ended Silva's seven-year undefeated mark, and became the first fighter to knock Silva out in an MMA match.

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Federal prosecutors are considering a new strategy for criminally charging Wall Street bankers who packaged and sold bad mortgage loans at the height of the housing bubble, according to a federal official familiar with the investigation.
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However, the failures at Stafford were repeatedly dismissed as an isolated case. In March 2009 Gordon Brown, then prime minister, told MPs: “I am assured by the Healthcare Commission [the then regulator]... that there is no equivalent case in all the other NHS hospitals across the country.”
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