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Eteplirsen's efficacy as seen in clinical studies and the absence of other treatments for DMD led to expectations that the FDA could speed up the drug's approval process, by possibly allowing the company to skip conducting a larger, late-stage trial.
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Families walked through the rain to shelters, televisionimages showed, as gusts of wind snapped branches from trees.Tourists left popular beach resort Puri. Officials broadcastcyclone warnings through loudspeakers, radio and television.
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These ruptures are real. Their costs are significant. Yet the men and women of the Republican Party seem to think the solution is to cut the budget of the Environmental Protection Agency and let the oil barons run rampant.
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Crowdsourcing was supposed to be the Big Idea that leveraged the interconnectedness of the Internet. Free information provided by netizens would be used for everything from restaurant rankings, local news, epidemiological studies, even climate change analysis. The results of crowdsourcing have been generally discouraging, however, although one emerging use case is proving to be the exception.

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In the second quarter, US Airways and Delta had difficultyraising yields, a measure of the average fare paid per mileflown. Delta's passenger yield was flat, while yield at USAirways fell 2.8 percent.
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The global market directly associated with electronic dancemusic is projected to be worth about $4.5 billion in 2013,according to the International Music Summit Business Report. Thesummit, held in Ibiza, a hot spot for electronic music, is aprominent gathering of dance music professionals.
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As Hargrove noted, Orcas are apex predators, like grizzly bears, gray wolves or African lions. They're nearly mythological creatures who hunt other large creatures of the sea (like dolphins, sea lions or even other whales) in groups. Marine biologists have learned in the recent decades that orcas may also be quite evolved, with a highly sensitized sense of family and community.
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This expanded jurisdiction came with a substantial increase in rule-writing responsibilities. Responding to the problems revealed by the financial crisis, Congress directed the Fed to improve the system of prudential regulation for large institutions by:
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They would divest from gun companies and others to make political points. They would launch aggressive audits and police Wall Street. They would save money by consolidating management of various pension funds.

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The anti-virus companies AVG and Avira themselves weren’t hacked, but rather the underlying DNS system that directs Internet traffic, as though the Internet phone number for the website were changed in a giant digital phonebook. It's nonetheless embarrassing, wrote security expert Graham Cluley.
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TOKYO, Oct 9 (Reuters) - Asian shares sagged and the dollarlanguished close to an 8-month low on Wednesday as the U.S.budget deadlock dragged on, further chipping away at investors'confidence that a deal will be reached before a mid-Octoberdeadline to avoid an historic debt default.
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Shame on Michael Bloomberg. In any 20 minutes last year, his personal fortune grew by more than an average wage slave earns over a lifetime of diligence and sweat. That doesn’t make him a bad person. But why does he go on about how the city cannot endure the economic burden of a living wage for working people?
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On Zarin’s lawn were the companies giving goodies away. Inside, all proceeds from any purchases went to St. Jude’s Children’s Research Hospital. And Mophie phone batteries, Trump wines, Spa Sonic, Warren-Tricomi products and gift certificates to Saks Fifth Avenue were all given away.

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The uncertainty emanating from Washington took the shine off a German election triumph for Angela Merkel which confirmed she would remain Europe's dominant leader as the continent tries to put its debt crisis to bed.
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After his second called strikeout in the fifth inning, A-Rod concluded that his night was over. As it turns out, his season will likely end Thursday as he may not join the Yankees in Houston for the final series of the season.
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The 76ers and Celtics are both in the same position: rebuilding mode. For coaches Brett Brown and Brad Stevens, that means a ton of faced-paced basketball with not a whole bunch of guys who are very good right now at accomplishing it.
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Vladimir Markin, a spokesman for Russia's Investigative Committee - its equivalent of the FBI - said there was a possibility that the remand orders would be lifted early as investigators clarify what roles those detained played in the protest.
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The core was taken from the West Antarctic Ice Sheet Divide, an area where there is little horizontal flow of the ice. This way, the scientists knew that the data were from a location that remained consistent over long periods. More than two miles deep, the core covers more than 68,000 years of climate history.

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The Idaho State Journal invites you to take part in the community conversation. But those who don't play nice may be uninvited. Don't post comments that are off topic, defamatory, libelous, obscene, racist, abusive, threatening or an invasion of privacy. We may remove any comment for any reason or no reason. We encourage you to report abuse, but the decision to delete is ours. Commenters have no expectation of privacy and may be held accountable for their comments.
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The interview was done at the Hispanic Society for a Drug Free Society, a drug treatment facility known as SERA. After Koch raised questions about financial mismanagement, the city cut off funding to the program.
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“If a young man’s injured, he’s not going to be able to take advantage of whatever opportunity he has,”Ryan added. “I’m certainly not going to put anyone out on the field if he’s injured.” 
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Pierre-Alain Beretta, the director and designer of the fireworks, said: “This year my challenge is to aim higher, to organise a show that is more beautiful than the last, more original, to always take pyrotechnics a step further. I learn more every year, which allows the show to evolve year by year.”
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Baldor has annual revenue above $200 million, over 800employees, and 200 trucks delivering produce, but the recentrise in rates won't have a direct impact because of the firm'sstrong cash position, Muzyk said. The company also has access toa credit line should it want to invest or expand, he said.

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"Regarding the verdict, we are gratified that the juryconcluded the design of the 2006 Camry did not contribute tothis unfortunate accident, affirming the same conclusion wereached after more than three years of careful investigation -that there was nothing wrong with the vehicle at issue in thiscase," a Toyota spokeswoman said in a statement.
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You could be forgiven for thinking that staying in a campsite in a tent or a mobile home would be a way of cutting costs. But in high season a mobile home is likely to cost at least £1,000 for a week on a big site in the Vendée, while a gîte could cost as little as £500 - both prices including the cost of the ferry fare.
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Top aides to Israeli Prime Minister Benjamin Netanyahu and Palestinian President Mahmoud Abbas began the talks over an iftar dinner - the evening meal with which Muslims break their daily fast during Ramadan - hosted by Kerry at the State Department.

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To make it easier for people to get the vaccine, the Ambulatory Care Network is adding staff and adding evening and weekend hours at its 15 locations, Acevedo said. The hospital has launched a campaign to encourage all of its own staff to get vaccinated and plans to have doctors host informational “flu talks” at local churches and community centers, she said.
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Sept 12 - Preliminary voting results show Michael Dell andSilver Lake have clinched shareholders' approval to go aheadwith the buyout, ending months of conflict and removing a cloudof uncertainty that has hung over the company.
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Since Abe took office following a lower house election victory in late December, aggressive monetary easing and government spending have helped pull the economy out of recession, as share prices surged and exports gained competitiveness thanks to a weaker Japanese yen.
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Zimmerman's lawyers argued he acted in self-defense the night of February 26, 2012, when, they say, Martin attacked Zimmerman inside a gated community in the central Florida town of Sanford. They accuse civil rights advocates of wrongly injecting the issue of race.
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White House spokesman Jay Carney told a press conference: “The President is happy that cooler heads at least seem to be prevailing in the House, that there at least seems to be a recognition that default is not an option.”

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Perry and Croft were both in the Royal Artillery but didn’t meet until many years later. “My agent, Ann [Callender], was David’s wife. She terrorised him to go to see me in plays and I got a small part in [BBC sitcom] Hugh and I, which David produced.” Perry gave Croft the scripts of a couple of episodes of his Home Guard comedy, Croft liked them and Dad’s Army was born.
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David Turbyfill, the father of Travis Turbyfill, one of the 19 hotshots, said he believes the report shows two factors contributed most to the deaths: ineffective communication and inadequate fire shelters. He thinks the report should erase any doubts about the crew's final actions.
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The A300 jet headed from Louisville, Ky., to Birmingham, Ala., landed in a field near the Birmingham-Shuttlesworth Airport around daybreak Wednesday, killing the two pilots on board and scattering wreckage over a wide area. The aircraft rained pieces of metal into front yards and sheared off a piece of one family's back deck.
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The tyre maker said in a statement its core shareholderswill discuss the possibility of dissolving their pact before itsexpiry in April 2015. In a separate statement, Pirelli saidClaudio Sposito and Paolo Fiorentino have become board members.
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The report highlights inconsistency in the provision of maternity services nationally in terms of variations in the models of service provided; resource allocations, and differences in the way quality and safety standards are monitored.

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Vrbata then scored the first of his three goals three minutes later when, after the Coyotes killed a Rangers’ power play, Derek Morris fired a shot from the blue line that Lundqvist knocked away. Vrbata got the bouncing puck and fired a shot that was also tipped away in front, but he grabbed the puck and flipped it into the back of the net.
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Reid has pledged not to expand the new rules beyond executive branch nominations. He argues such nominees should be approved by a simple majority. "This does not affect lifetime appointments. It doesn't affect substantive legislation. It allows the president to have his team -- this president and those in the future. And that's the way it should be," he said.
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Yet each year for the past few has opened with forecasts that this will be the one that the U.S. economy grows at 3% or better; each year so far has disappointed. CBO estimates that U.S. output of goods and services will be below its potential until 2017. Unemployment remains at levels once seen only in recessions.
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Not only did Americans score poorly compared to many international competitors, the findings reinforced just how large the gap is between the nation's high- and low-skilled workers and how hard it is to move ahead when your parents haven't.

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Liberty, which also holds a controlling stake in Belgiancable operator Telenet and Ziggo's Dutch rival UPC,acquired its first 12.65 percent of Ziggo when Barclays was left with shares it failed to place for previous ownersCinven and Warburg Pincus.
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If you run your own business, are self-employed or spend money on education to boost your career, then many of your expenses may be tax deductible. Make sure you put your receipts in an easy-to-find filing system so you can claim them when you file your taxes next year. If your employer offers flexible spending accounts for health care costs, you also want to make sure to keep eligible receipts for doctor visits, pharmaceuticals and other health-related expenses. You often have until April 15 to file those claims.
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Within four days of installation, the wiretap equipment picked up more than 260 pertinent calls that constituted evidence of professional gambling. Detective Paul Moore identified Terri Hernandez as a low-ranking member of an illegal sports gambling operation, according to the affidavit. Hovanesian was labeled as the bookmaker, and Terri Hernandez told police he stopped by to check figures every Sunday and Monday.
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Actor Jason Schwartzman will host the program, which will unfold live at Pier 36 in New York; details will be shared later this month on how fans can apply for tickets. Spike Jonze is the show's creative director. Guests include Eminem, Lady Gaga, Arcade Fire and YouTube-fueled phenomenons such as the music-video collective CDZA and violinist Lindsey Stirling. Other as-yet-unannounced acts will provide taped performances from cities as far-flung as Seoul and Moscow, YouTube's way of emphasizing the global nature of its audience.